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If successful, MariTide could challenge the Novo Nordisk/Eli Lilly duopoly which the report notes holds 57.4% of the market and reshape the competitive landscape by 20292031

GCLC-KO mice showed activation of C1q, which triggers engulfment of neurons by microglia, and disease-associated-microglia (DAM), suggesting that activation of microglia is linked to the neuronal loss