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The intermediate is subsequently transported into synaptic vesicles via the vesicular monoamine transporter (VMAT) and hydroxylated by dopaminehydroxylase (DBH) to yield methylnorepinephrine ( panel 2 )

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The culture media was substituted by those including DMSO or ZIL and the cells were cultured until the control sample (which does not contain the solvents) became 80% confluent

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