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Diagnosis requires full blood count showing macrocytic anaemia, serum B12 measurement below 148 pmol/L, and intrinsic factor antibodies to confirm pernicious anaemia
This is also in line with a study in older 16 months old APOE-TR mice which found the same pattern of decreased LCAs and increased SCAs in E4s compared to E3s, particularly in males (Shang et al., 2020)
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