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TB001 treatment also reduced the body weight of recipients ( P = 0.0002, Figure 1E ) without affecting the weight of the transplanted kidneys, as evidenced by a higher graft-to-body weight ratio in the TB001 group ( P = 0.037, Figure 1F )

Clinical evidence indicates that exenatide effectively reduces body weight and enhances metabolic control, with subgroup analyses confirming that these benefits are also observed in older adults [26, 71, 72]

Oral Semaglutide Reduces HbA 1c and Body Weight in Patients with Type 2 Diabetes Regardless of Background Glucose-Lowering Medication: PIONEER Subgroup Analyses