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THF plays an important role in DNA synthesis, so reduced availability of THF results in ineffective production of cells with rapid turnover, in particular red blood cells, and also intestinal wall cells which are responsible for absorption
What oral dose produces equivalent effects to parenteral
No evidence-based guidelines exist for female-specific dosing, safety, or outcomes
While formal drug interaction studies are limited, AOD-9604 can often be safely combined with other therapies under proper medical supervision
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