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When GLP-1 binds to its receptor, it activates Akt, which subsequently inhibits GSK3 and reduces the accumulation of harmful proteins, such as -synuclein
and for adults with overweight in the presence of at least one weight-related health condition like high blood pressure or heart disease
These conditions often develop silently, though if untreated, they can lead to serious health complications such as stroke, heart disease and kidney failure
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