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Cagrilintide is a long-acting amylin analog that works on the satiety pathway, the signal that tells your brain you are full and keeps you full, so appetite quiets and weight loss becomes sustainable rather than a constant fight

Tirzepatide carries the highest risk of diarrhea in type 2 diabetes patients, while semaglutide has the highest risk for constipation

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In Experiment 1, acute semaglutide robustly disrupted alcohol discrimination, as evidenced by significant reductions in alcohol-appropriate responding at multiple doses in both sexes