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In summary, these nanoscale systems enhance SOD activity through diverse mechanismsincluding gene delivery to induce endogenous expression, activation of upstream signaling pathways for indirect regulation, or direct mimicry of enzymatic catalytic activity to scavenge ROSall demonstrating superior targeting and sustained efficacy compared to traditional antioxidants in IRI therapy
CXCL11 promotes tumor progression by the biased use of the chemokine receptors CXCR3 and CXCR7
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