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A volume of 4-NPG (final concentration of 1 mM) was added to the reaction and decrease in absorbance at 305 nm was recorded on an Envision multilabel plate reader (Perkin Elmer)

doi: 10.1016/S0021-9258(18)67324-7 23 HolstJJOrskovCNielsenOVSchwartzTW

The SURMOUNT-1 trial studied the effects of tirzepatide in adults with obesity and found: People taking 5 mg of tirzepatide lost about 15% of their body weight

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