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Vitamins and essential metals are essential for life and their lack can cause adverse responses (plotted on the vertical axis), as can their excess, giving rise to a U-shaped dose-dependence curve
2060204) and Shanghai Committee of Science and Technology (Grant No
Werry, E
Research indicates that concentrations of up to 2% in leave-on products (such as lotions and serums) are well-tolerated by most skin types, showing no significant adverse effects or irritation in long-term dermatological studies
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